The Science

hydrogen water antioxidant
The Science

Hydrogen Water as a Novel Antioxidant

Molecular Hydrogen as a Novel Antioxidant: Overview of the Advantages of Hydrogen for Medical Applications Below is an excerpt from the study “Molecular Hydrogen as a Novel Antioxidant” that is most meaningful for our purposes. You may find the link to the full text at the bottom of this page. Shigeo Ohta from Department of Biochemistry and Cell Biology, Institute of Development and Aging Sciences, Graduate School of Medicine, Nippon Medical School, Kawasaki, Japan Abstract Molecular hydrogen (H2) was believed to be inert and nonfunctional in mammalian cells. We overturned this concept by demonstrating that H2 reacts with highly reactive

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Nitric Oxide Supplement
The Science

Benefits of Nitric Oxide Supplements

From Three Studies It is established scientifically (Nobel Prize 1998) that nitric oxide is a compound in the body that dilates blood vessels and stimulates the release of hormones, such as insulin and human growth hormone. Nitric oxide boosters are available as a supplement in the form L-citrulline and L-arginine, et al, commonly. Multiple clinical trials by researchers related to the benefits of nitric oxide and its effectiveness have been performed. Presented here are some of those results. Improves Heart Health According to research published in Biochemical and Biophysical Research Communications in the article, Oral supplementation with a combination of

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Vinitrox - Nitic Oxide Booster
The Science

Acute Dose of ViNitrox Improves Endurance Performance

Abstract Polyphenols are thought to be an interesting ergogenic aid for exercise and recovery. However, most studies regarding the effects of polyphenols investigated several days of supplementations. The present work aimed to study the effects of an acute intake of grape and apple polyphenols (ViNitrox) on the capacity to maintain intense exercise, here named endurance performance. Forty-eight physically active men (31 ± 6 years) were included in this study. During the two testing sessions, volunteers completed an endurance test at a high percentage of their maximal aerobic power and time to exhaustion was measured. Respiratory and pain parameters were also

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molecular-hydrogen
The Science

Molecular Hydrogen Affects Body Composition

Molecular hydrogen affects body composition, metabolic profiles, and mitochondrial function in middle-aged overweight women Abstract Background Molecular hydrogen (H2) effectively treats obesity-related disorders in animal models, yet no studies have investigated the effectiveness and safety of H2 for improving biomarkers of obesity in humans. Aim In this double blind, placebo-controlled, crossover pilot trial, we evaluated the effects of H2 intervention on body composition, hormonal status, and mitochondrial function in ten (n = 10) middle-aged overweight women. Methods Volunteers received either hydrogen-generating minerals (supplying ~6 ppm of H2 per day) or placebo by oral administration of caplets for 4 weeks. The

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The Science

Molecular Hydrogen & Immune System

Effects of molecular hydrogen-dissolved alkaline electrolyzed water on intestinal environment in mice Abstract Increasing evidence indicates that molecular hydrogen-dissolved alkaline electrolyzed water (AEW) has various physiological activities such as antioxidative activity. Gut microbiota are deeply associated with our health through a symbiotic relationship. Recent reports have described that most gastrointestinal microbial species encode the genetic capacity to metabolize molecular hydrogen, meaning that molecular hydrogen might affect the gut microbial composition. Nevertheless, AEW effects on gut microbiota remain unknown. This study investigated AEW effects on the intestinal environment in mice, including microbial composition and short-chain fatty acid contents. After mice were

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ghrelin in brain diseases
The Science

Mental Focus & Clarity

The neurological effects of ghrelin in brain diseases: Beyond metabolic functions Highlights of this study from Qingdao University Ghrelin is attracted more attention for its neuroprotective and neurogenesis roles. Ghrelin modulates numerous neuronal behaviors in pathological conditions. Ghrelin promotes neurogenesis through stimulating neural stem/progenitor cells proliferation, differentiation and migration. Ghrelin regulates synaptic plasticity and electrophysiological activity which may influence advanced brain functions. Abstract Ghrelin, a peptide released by the stomach that plays a major role in regulating energy metabolism, has recently been shown to have effects on neurobiological behaviors. Ghrelin enhances neuronal survival by reducing apoptosis, alleviating inflammation and oxidative

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hydrogen water & depression
The Science

Effects of Hydrogen Water on Depression

Effects of hydrogen-rich water on depressive-like behavior in mice Abstract Emerging evidence suggests that neuroinflammation and oxidative stress may be major contributors to major depressive disorder (MDD). Patients or animal models of depression show significant increase of proinflammatory cytokine interleukin-1β (IL-1β) and oxidative stress biomarkers in the periphery or central nervous system (CNS). Recent studies show that hydrogen selectively reduces cytotoxic oxygen radicals, and hydrogen-rich saline potentially suppresses the production of several proinflammatory mediators. Since current depression medications are accompanied by a wide spectrum of side effects, novel preventative or therapeutic measures with fewer side effects might have a promising

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hydrogen wter bathing
The Science

Hydrogen Water & Aging Effects of the Skin

Hydrogen-rich electrolyzed warm water represses wrinkle formation against UVA ray together with type-I collagen production and oxidative-stress diminishment in fibroblasts and cell-injury prevention in keratinocytes ABSTRACT Hydrogen-rich electrolyzed warm water (HW) was prepared at 41ºC and exhibited dissolved hydrogen (DH) of 1.13 ppm and an oxidation-reduction potential (ORP) of -741 mV in contrast to below 0.01 ppm and +184 mV for regular warm water (RW). Fibroblasts OUMS-36 and keratinocytes HaCaT were used to examine effects of HW against UVA-ray irradiation. Type-I collagen was synthesized 1.85- to 2.03-fold more abundantly by HW application for 3-5 days than RW in OUMS-36 fibroblasts,

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hydrogen
The Science

Hydrogen Acts as a Therapeutic Antioxidant

Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals Oxidative stress arises from the strong cellular oxidizing potential of excess reactive oxygen species (ROS), or free radicals. Mostofthesuperoxide anion radical (O2) produced is generated in mitochondria by electron leakage from the electron transport chain and the Krebs cycle. O2 is also produced by metabolic oxidases, including NADPH oxidase and xanthine oxidase. Superoxide dismutase converts O2 into hydrogen peroxide (H2O2), which is detoxified into H2O by either glutathione peroxidase or catalase. Excess O2 reduces transition metal ions such as Fe3+ and Cu2+ (ref. 2), the reduced forms of

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hydrogen-water-study
The Science

Hydrogen Water & Muscle Fatigue

Pilot study: Effects of drinking hydrogen-rich water on muscle fatigue caused by acute exercise in elite athletes Abstract Background: Muscle contraction during short intervals of intense exercise causes oxidative stress, which can play a role in the development of overtraining symptoms, including increased fatigue, resulting in muscle microinjury or inflammation. Recently it has been said that hydrogen can function as antioxidant, so we investigated the effect of hydrogen-rich water (HW) on oxidative stress and muscle fatigue in response to acute exercise. Methods: Ten male soccer players aged 20.9 ± 1.3 years old were subjected to exercise tests and blood sampling.

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