REDEFINING HEALTH
FROM THE INSIDE OUT

Introduction
Endothelial glycocalyx is a layer of sugar molecules that lines the inside of blood vessels and protects them from damage. Chronic kidney disease (CKD) is a condition in which the kidneys are damaged and cannot filter blood as well as they should. Fucoidan is a sulfated polysaccharide found in brown seaweed and sold as a dietary supplement that has been shown to have anti-inflammatory, anti-tumor, and anti-viral properties[1]. Fucoidan is one of the primary ingredients found in our dietary supplement, Endocalyx Pro^TM. A recent study published in a special issue of International Journal of Molecular Sciences suggests that a dietary supplement containing fucoidan preserves endothelial glycocalyx through ERK/MAPK signaling and protects against damage induced by CKD serum. In this article, we’ll take a closer look at fucoidan and its potential benefits for people with CKD.

Chronic kidney disease is a serious health condition and requires medical diagnosis and treatment. This article does not intend to offer advice to diagnose or treat any health condition. You should always talk to your doctor for medical advice. Statements in this article have not been evaluated by the FDA.

What is endothelial glycocalyx?
Endothelial glycocalyx is a layer of sugar molecules that lines the inside of blood vessels and protects them from damage. It plays an important role in regulating blood flow and preventing blood clots. When the glycocalyx is damaged, it can lead to inflammation, oxidative stress, and other health problems[2].

What is fucoidan?
Fucoidan is a sulfated polysaccharide found in brown seaweed. It has been shown to have anti-inflammatory, anti-tumor, and anti-viral properties[1]. Fucoidan has also been found to have a number of other potential health benefits, including improving gut health, boosting the immune system, and reducing the risk of heart disease[3].

What is chronic kidney disease?
Chronic kidney disease (CKD) is a condition in which the kidneys are damaged and cannot filter blood as well as they should. This can lead to a buildup of waste products in the blood, which can cause a range of health problems. CKD is a common condition, affecting millions of people around the world.

How does fucoidan preserve endothelial glycocalyx?
According to the study in International Journal of Molecular Sciences, a dietary supplement containing fucoidan preserves endothelial glycocalyx through ERK/MAPK signaling and protects against damage induced by CKD serum.

How does fucoidan protect against damage induced by CKD serum?
The study suggests that fucoidan may also protect against damage induced by CKD serum. CKD serum is a type of blood serum that is associated with kidney damage. By protecting against this type of damage, fucoidan may help to improve kidney function and reduce the risk of complications associated with CKD such as heart disease and anemia.

How can the supplement be used to help people with chronic kidney disease?
The study also suggests that a supplement containing fucoidan could be used to help people with chronic kidney disease. Our Endocalyx Pro is a dietary supplement that contains fucoidan and is designed to support endothelial glycocalyx health. However, it’s important to note that more research is needed to determine the safety and effectiveness of fucoidan for this purpose. If you’re interested in trying Endocalyx Pro, it’s a good idea to talk to your doctor first to make sure it’s safe for you.