July, 2020 | NuLife Sciences

The Science

Effects of Hydrogen Water on Depression

Effects of hydrogen-rich water on depressive-like behavior in mice Abstract Emerging evidence suggests that neuroinflammation and oxidative stress may be major contributors to major depressive disorder (MDD). Patients or animal models of depression show significant increase of proinflammatory cytokine interleukin-1β (IL-1β) and oxidative stress biomarkers in the periphery or central nervous system (CNS). Recent studies show that hydrogen selectively reduces cytotoxic oxygen radicals, and hydrogen-rich saline potentially suppresses the production of several proinflammatory mediators. Since current depression medications are accompanied by a wide spectrum of side effects, novel preventative or therapeutic measures with fewer side effects might have a promising

The Science

Hydrogen Water & Aging Effects of the Skin

Hydrogen-rich electrolyzed warm water represses wrinkle formation against UVA ray together with type-I collagen production and oxidative-stress diminishment in fibroblasts and cell-injury prevention in keratinocytes ABSTRACT Hydrogen-rich electrolyzed warm water (HW) was prepared at 41ºC and exhibited dissolved hydrogen (DH) of 1.13 ppm and an oxidation-reduction potential (ORP) of -741 mV in contrast to below 0.01 ppm and +184 mV for regular warm water (RW). Fibroblasts OUMS-36 and keratinocytes HaCaT were used to examine effects of HW against UVA-ray irradiation. Type-I collagen was synthesized 1.85- to 2.03-fold more abundantly by HW application for 3-5 days than RW in OUMS-36 fibroblasts,

The Science

Hydrogen Acts as a Therapeutic Antioxidant

Hydrogen acts as a therapeutic antioxidant by selectively reducing cytotoxic oxygen radicals Oxidative stress arises from the strong cellular oxidizing potential of excess reactive oxygen species (ROS), or free radicals. Mostofthesuperoxide anion radical (O2) produced is generated in mitochondria by electron leakage from the electron transport chain and the Krebs cycle. O2 is also produced by metabolic oxidases, including NADPH oxidase and xanthine oxidase. Superoxide dismutase converts O2 into hydrogen peroxide (H2O2), which is detoxified into H2O by either glutathione peroxidase or catalase. Excess O2 reduces transition metal ions such as Fe3+ and Cu2+ (ref. 2), the reduced forms of

The Science

Hydrogen Water & Muscle Fatigue

Pilot study: Effects of drinking hydrogen-rich water on muscle fatigue caused by acute exercise in elite athletes Abstract Background: Muscle contraction during short intervals of intense exercise causes oxidative stress, which can play a role in the development of overtraining symptoms, including increased fatigue, resulting in muscle microinjury or inflammation. Recently it has been said that hydrogen can function as antioxidant, so we investigated the effect of hydrogen-rich water (HW) on oxidative stress and muscle fatigue in response to acute exercise. Methods: Ten male soccer players aged 20.9 ± 1.3 years old were subjected to exercise tests and blood sampling.

The Science

Hydrogen Water Stimulates the Growth of Anaerobic Microflora

ABSTRACT* Selective stimulation of the growth of anaerobic microflora in the human intestinal tract by electrolyzed reducing water (hydrogen water). Department of Physiology of Microorganisms, Biology Faculty, Lomonosov Moscow State University, 119992 Moscow, Russia. Vorobjeva NV, Med Hypotheses. 2005;64(3):543 -6. 96-99% of the “friendly” or residential microflora of intestinal tract of humans consists of strict anaerobes and only 1-4% of aerobes. Many diseases of the intestine are due to a disturbance in the balance of the microorganisms inhabiting the gut. The treatment of such diseases involves the restoration of the quantity and/or balance of residential microflora in the intestinal tract.