NuLife Archive

what is glycocalyx?
The Science

What is Glycocalyx?

(image credit: van den Berg, Vink & Spaan, Circulation Research 2003, 92:592-594) Glycocalyx is the gel-like lining of the capillaries and all other blood vessels. Its integrity is essential to the healthy function of all cells, organs and body systems. This lining protects the inside walls of the capillaries and enables the transfer of nutrients and waste removal from vital organs. The gel-like substance that is glycocalyx is a free form matrix made up of starches, fluid, ions, and other stuff. An example of a free form matrix familiar to most people is gelatin desserts which are made of starch

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glycocalyx-function
The Science

Glycocalyx: Function & Definition

The Function of Glycocalyx in Blood Vessels and Capillaries Glycocalyx serves as the mediator for cell-to-cell interactions and protects the cell membrane from fluid shearing forces allowing the cell membrane to maintain its integrity. Glycocalyx is a highly hydrated fibrous meshwork within blood vessels and capillaries that covers the endothelial cells. This layer functions as a barrier between a cell and its surroundings.  Specifically, the endothelial glycocalyx regulates vascular permeability, modulates the interaction between blood and endothelial cells. The generic structural components of glycocalyx are proteoglycans and glycoproteins, other compositional components are determined by the specific cell type and other

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healthy-glycocalyx
The Science

Endothelial Glycocalyx & Declining Health

Endothelial glycocalyx has been shown to be an integral part of the microvascular system. Without a healthy glycocalyx layer inside the blood vessels and capillaries systems that are required for good health may not function correctly. You may look and feel healthy, but your microvascular system could be in a much different state. Organ starvation is one reason that declining health and diseases begin in the body. When the capillaries begin to lose their function, vital organs don’t receive the nutrients needed to be healthy… the silent spiral of health decline begins. Conditions that can be caused by organ starvation

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crystal ball

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