Perturbation of the microvascular glycocalyx and perfusion in infants after cardiopulmonary bypass
Abstract Objective Perturbation of the endothelial glycocalyx is discussed in the pathogenesis of complications related to cardiopulmonary bypass. We evaluated the effects of cardiopulmonary bypass on the microcirculation and the microvascular endothelial glycocalyx of infants undergoing surgery for congenital cardiac defects. Methods The microcirculation was visualized at the ear conch using Sidestream dark field imaging before surgery (T0), after…